SOMATIC HYPERMUTATION IN T-INDEPENDENT (TI) AND T-DEPENDENT (TD) IMMUNE RESPONSES. • 38
نویسندگان
چکیده
منابع مشابه
T cell–independent development and induction of somatic hypermutation in human IgM+IgD+CD27+ B cells
IgM(+)IgD(+)CD27(+) B cells from peripheral blood have been described as circulating marginal zone B cells. It is still unknown when and where these cells develop. These IgM(+)IgD(+)CD27(+) B cells exhibit somatic hypermutations (SHMs) in their B cell receptors, but the exact nature of the signals leading to induction of these SHMs remains elusive. Here, we show that IgM(+)IgD(+)CD27(+) B cells...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1996
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199604001-00057